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ICU Trials is a quick pocket reference for both the novice and seasoned critical care clinician. This app does not replace the original manuscript of these landmark critical care trials – instead, it serves as a fast reference and learning tool for some of the most important ICU trials over a wide range of specialties.

Each entry contains a short one-liner about the critical care trial and key points, which includes only the most pertinent details, such as inclusion/exclusion criteria, treatment protocols, pertinent endpoints and findings, as well as expert commentary regarding key subgroup analyses or limitations to the trial.

Want to send a colleague a citation? Use the "Share Trial" button to send a PubMed link via email. Using this feature, it’s incredibly easy to share pivotal critical care trials with students, residents, and other colleagues.

The database features 83 landmark trials related to: ARDS, cardiac arrest, DVT/PE, delirium, glycemic control, heart failure, hemorrhage, meningitis, nephroprotection, nutrition, pneumonia, sedation, seizure, sepsis/shock, spinal cord injury, stroke, and subarachnoid hemorrhage – with more trials and topics to be added on a regular basis!

This app is designed and maintained by Sean P. Kane, PharmD, BCPS -- a clinical pharmacist specializing in critical care with a background in information technology and application development.

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Primary: Applications

Secondary: Medical

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Version History

Launched Jan 29, 2014 (almost 6 years ago).

Releasing new versions every 10 months, on average.

Jan 18
Version 3.1.4

Additional updates to support Android Pie (9.0); integration of the newest trial database version (Oct 2018) without having to run an in-app update

Jan 14
Version 3.1.3

Additional bug fixes specific to Android Pie (9.0) crashes; new permission request for external storage is intended to solve some of these crashes

Oct 15
Version 3.1.2

Update addressing Android Pie (9.0) crashes -- thank you to all users who submitted bug reports to track down the problem!

Oct 13
Version 3.1.1

Further bug fixes specifically for Android Pie (9.0) crashes

Oct 13
Version 3.1

Major bug fix for Android Pie (9.0) that was causing the app to crash

Mar 23
Version 3.0

Major update including a number of bug fixes & features -- "related trials" links at the end of each trial summary, notifications of database updates, update to the most recent (March 2018) database update, and more!

Jan 28
Version 2.0

We've made significant upgrades to the high-res graphics, user interface, and app performance. The app requires new permissions -- as part of the update, ICU Trials will now automatically prompt you to update the trial database from within the app. This functionality allows for more frequent landmark trial updates!
With the 2.0 update, we also added five new landmark trials: SLEAP (Mehtra 2012), SHOCK (Hochman 1999), TTM (Nielsen 2013), CRISTAL (Annane 2013), and Esteban 2004.

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